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Researchers at Pacific Northwest National Laboratory have discovered the basis for a new method to accurately and quickly detect tumor necrosis factor alpha, a biomarker for many problems, including as HIV infection, graft rejection and rheumatoid arthritis. First, an appropriate bodily fluid sample is mixed with a label consisting of polyguanine attached to silica nanoparticles (large particles with red squiggles). This label attaches itself to the tumor necrosis factor alpha (diamond) in the sample. Then, the labeled factor binds with the antibodies on the outer layer of the sensor's carbon nanotubes.

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Document Title: Tumor Necrosis Factor Alpha Detection
Category: EMSL (William R. Wiley Environmental Molecular Sciences Laboratory)
Media Type: Graphics
Date of Image/Photo: April 2006
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URL of this page: http://picturethis.pnl.gov/picturet.nsf/by+id/AMER-6P.39J

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