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The circular design of the nanoESI multi-emitter (shown here with 20 individual nano-electrosprays) solves the field-shielding problem in ESI emitter array operation. The design provides each emitter with the same electric field, causing uniform electrosprays providing higher spray current and greatly improved ionization efficiencies compared to standard single emitter sources.

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Document Title: Nano-electrospray interface multi-emitter
Category: Biomolecular Systems and Science
Media Type: Photos
Date of Image/Photo: February 2009
Background: The Ultrasensitive Electrospray Ionization Mass Spectrometry Source and Interface, winner of a 2009 R&D 100 Award, comprises a multi-nanoelectrospray ionization source and a multi-inlet MS interface. This technology provides ionization efficiencies that were before only achievable from very-low-flow-rate, specialized separations and enables it to be used with common, higher-flow-rate analyses. The Ultrasensitive ESI-MS Source and Interface provides at least a 40-fold increase in MS sensitivity relative to commercially available instrumentation. Results include greatly improved operation, sensitivity, and quantitation for liquid samples and from liquid chromatography separations. Applications range from analyses of materials from pharmaceuticals to petrochemicals.
URL of this page: http://picturethis.pnl.gov/picturet.nsf/by+id/DRAE-7VVRVY

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